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Cat. No.: HY-206972

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Poly(3-hydroxybutyrate)

Poly (3-hydroxybutyrate) is a bacterially derived (R)-3-hydroxybutyrate homopolymer and a degradable biomaterial. Poly (3-hydroxybutyrate) degrades in vivo via lipases and esterases, breaking down into 3-Hydroxybutyric acid (HY-113378). Poly (3-hydroxybutyrate) can be compounded with 15% Hydroxyapatite (HA) (HY-D0835A) or 7.5-10% nanobioglass for use as a bone scaffold.

For research use only. We do not sell to patients.

CAS No.: 26063-00-3
Formula: C₄H₈O₃
Molecular Weight:104.10

Storage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Poly(3-hydroxybutyrate) Chemical Structure

CAS No.: 26063-00-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Pure Poly (3-hydroxybutyrate) scaffolds support the adhesion, proliferation and differentiation of rabbit bone marrow cells, and are non-tumorigenic and non-genotoxic, but the proliferation rate is slower than that of modified scaffolds^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Poly(3-hydroxybutyrate) (implant; single administration) completely close surgically created anterior skull base defects in minipigs within 9 months while undergoing continuous biodegradation^[1].
Poly(3-hydroxybutyrate) (implant; single administration) support bone formation and blood vessel development without inflammation or rejection in surgically created cranial defects of adult male rats within 12 weeks^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 26063-00-3
Appearance Solid
Molecular Weight 104.10
Formula C₄H₈O₃
SMILES

CC(O)CC(O)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Dariš B, et al. Poly(3-hydroxybutyrate): Promising biomaterial for bone tissue engineering. Acta pharmaceutica (Zagreb, Croatia). 2020 Mar 01;70(1):1-15. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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