Hydroxylapatite (<50 nm)
Based on 1 Customer Validation
Hydroxylapatite (Hydroxyapatite) (<50 nm) is a natural form of calcium phosphate and is the main mineral component of bones and teeth. Hydroxylapatite (<50 nm) can stimulate the expression and secretion of collagen in primary human dermal fibroblasts. Hydroxylapatite (<50 nm) has good biocompatibility, bioactivity, and bone conductivity, making it suitable for targeted drug or nucleic acid delivery. Hydroxylapatite (<50 nm) can be used in research on osteoarthritis, gout, and atherosclerosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.05%
- CAS 番号: 1306-06-5
- 分子式: Ca5HO13P3
- 分子量:502.31
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
体外実験
Hydroxylapatite is suspended in 0.2 μm filtered purified water, sonicated and vortexed for 5 min and collected by centrifugation at 16,000 g for 1 min. The procedure was repeated five times to wash the Hydroxylapatite particles and a 40 mg/mL stock suspension was prepared in 0.1 M NaCl before administering to cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1306-06-5
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性状 Solid
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分子量 502.31
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分子式 Ca5HO13P3
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Color White to off-white
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SMILES
O[Ca][Ca][Ca][Ca][Ca]P1(OOO1)=O.O=P2(P3(OOO3)=O)OOO2
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別名
Hydroxyapatite (<50 nm)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Rakshit M, et al. Hydroxyapatite Particles Induced Modulation of Collagen Expression and Secretion in Primary Human Dermal Fibroblasts. Int J Nanomedicine. 2020 Jul 13;15:4943-4956. [Content Brief]
[2]. Yongjia Liu, et al. Hydroxyapatite-Bovine Serum Albumin-Paclitaxel Nanoparticles for Locoregional Treatment of Osteosarcoma. Adv Healthc Mater. 2020 Nov 9;e2000573. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)