Heparastatin
Heparastatin is a heparanase inhibitor.
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- CAS No.: 153758-25-9
- Formule: C8H11F3N2O5
- Masse moléculaire:272.18
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
heparanase[1].
Addition of 100 μM of Heparastatin (SF4) completely inhibits the enzyme activity of heparanase at a concentration of 0.15 μg/mL in an in vitro degradation assay. Addition of Heparastatin during the transition process does not affect the phenotypic change of TGF-β-treated cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 153758-25-9
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Masse moléculaire 272.18
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Formule C8H11F3N2O5
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SMILES
O=C([C@H]1CN[C@H](NC(C(F)(F)F)=O)[C@@H](O)[C@H]1O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
Influence of a heparanase inhibitor on TGF-β3-induced EMT of NMuMG cells. NMuMG cells are cultured with 1 ng/mL TGF-β3 together with 10 or 100 μM Heparastatin (SF4) for 48 h[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Heparastatin Related Classifications
HY-100899 Related Classifications
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