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United States

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Cat. No.: HY-169249

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Aekatperone

(Synonyms: Z1620764636)

Aekatperone is a reversible K_ATP channel inhibitor, with an IC₅₀ of 9 μM. Aekatperone can be used for the research of congenital hyperinsulinism (CHI).

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₂₀H₂₅N₅O₂S
Masse moléculaire:399.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Aekatperone Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Aekatperone is a reversible K_ATP channel inhibitor, with an IC₅₀ of 9 μM. Aekatperone can be used for the research of congenital hyperinsulinism (CHI)^[1].

Chemical Information

Masse moléculaire 399.51
Formule C₂₀H₂₅N₅O₂S
SMILES

O=S(C(C=CC=C1)=C1CN2C=CN=C2)(NC3=NNC(CC4CCCCC4)=C3)=O
Synonyms

Z1620764636
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. ElSheikh A, et al. AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone. bioRxiv [Preprint]. 2024 Sep 5:2024.09.05.611490. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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