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Cat. No.: HY-105969

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Dichloromethotrexate

(Synonyms: NSC-29630; 3',5'-Dichloromethotrexate)

Dichloromethotrexate (NSC-29630), an orally active antitumor agent, shows antitumor effect against L1210 leukemia and C3H lymphosarcoma in mice.

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CAS No.: 528-74-5
Formule: C₂₀H₂₀Cl₂N₈O₅
Masse moléculaire:523.33

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Dichloromethotrexate Chemical Structure

CAS No.: 528-74-5

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Activité biologique

Description

Dichloromethotrexate (NSC-29630), an orally active antitumor agent, shows antitumor effect against L1210 leukemia and C3H lymphosarcoma in mice^[1].

Chemical Information

CAS No. 528-74-5
Masse moléculaire 523.33
Formule C₂₀H₂₀Cl₂N₈O₅
SMILES

NC1=NC(N)=NC2=NC=C(CN(C3=C(C=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3Cl)Cl)C)N=C12
Synonyms

NSC-29630; 3',5'-Dichloromethotrexate
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. FREI E 3rd, et al. CLINICAL STUDIES OF DICHLOROMETHOTREXATE (NSC 29630). Clin Pharmacol Ther. 1965 Mar-Apr;6:160-71. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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