NLRP3-IN-70
NLRP3-IN-70 (Compound 5m) is an NLRP3 inflammasome inhibitor with low oral bioavailability. NLRP3-IN-70 can directly bind to the NACHT domain of the NLRP3 protein and block the interaction of NLRP3 and ASC, thus inhibiting ASC oligomerization and NLRP3 inflammasome assembly. NLRP3-IN-70 can be used in the research of sepsis and nonalcoholic steatohepatitis.
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- CAS No.: 1997362-01-2
- Formule: C23H23NO5
- Masse moléculaire:393.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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NLRP3 1.34 μM (Kd) |
Chemical Information
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CAS No. 1997362-01-2
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Masse moléculaire 393.43
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Formule C23H23NO5
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SMILES
O=C(C1=C(C2=C3C4=C(C(C)(CCC4)C)C=C2)OC=C1C(N5CCOCC5)=O)C3=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NLRP3-IN-70 Related Classifications
HY-172134 Related Classifications
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