p-Hydroxybenzaldehyde-d5
p-Hydroxybenzaldehyde-d5 is the deuterium labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.
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- CAS No.: 298704-22-0
- Formule: C7HD5O2
- Masse moléculaire:127.15
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 298704-22-0
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Unlabeled Cas 123-08-0
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Masse moléculaire 127.15
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Formule C7HD5O2
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SMILES
O=C([2H])C1=C([2H])C([2H])=C(C([2H])=C1[2H])O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Zhang J, et al. The Effect of 4-hydroxybenzaldehyde on the γ-aminobutyric Acid Type A Receptor. Malays J Med Sci. 2017 Mar;24(2):94-99. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)