PAR 4 (1-6) TFA
PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist.
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- Formule: C28H41N7O9.xC2HF3O2
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
PAR4[1]
PAR 4 (1-6) (GYPGQV) stimulats [3H]-thymidine incorporation in SMC. At 500 μM, the peptide increases DNA synthesis 2.5 fold above controls. A comparable mitogenic effect is obtained after stimulation of the SMC by 10 nM thrombin or 100 μM SFLLRN, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Formule C28H41N7O9.xC2HF3O2
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Synonyms
GYPGQV TFA
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. H Andersen, et al. Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11189-93. [Content Brief]
[2]. E Bretschneider, et al. Evidence for functionally active protease-activated receptor-4 (PAR-4) in human vascular smooth muscle cells. Br J Pharmacol. 2001 Apr;132(7):1441-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PAR 4 (1-6) TFA Related Classifications
HY-P1313A Related Classifications
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