PF-06250112
PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC50s of 0.9 nM and 1.2 nM, respectively.
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- CAS No.: 1609465-89-5
- Formule: C22H20F2N6O2
- Masse moléculaire:438.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
IC50: 0.5 nM (BTK), 0.9 nM (BMX), 1.2 nM (TEC)[1]
Chemical Information
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CAS No. 1609465-89-5
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Masse moléculaire 438.43
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Formule C22H20F2N6O2
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SMILES
O=C(N)C1=C(N(N=C1C2=CC=C(C=C2)OC3=CC=C(C=C3F)F)[C@@H]4CN(CCC4)C#N)N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)