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United States

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Cat. No.: HY-184933

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PIN1-IN-8

PIN1-IN-8 (Compound T41) is a covalent inhibitor of Pin1, with IC₅₀ values of 0.13 μM and 0.02 μM against purified Pin1 and Pin1 enzymatic activity, respectively. PIN1-IN-8 can be used in triple-negative breast cancer research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₁₅H₁₇NO₅S
Masse moléculaire:323.36

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PIN1-IN-8 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Chemical Information

Masse moléculaire 323.36
Formule C₁₅H₁₇NO₅S
SMILES

O=C(NC1CS(CC1)(=O)=O)/C=C\C(OCC2=CC=CC=C2)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Tian M, et al. Structure-Based Discovery of (E)- and (Z)-4-Oxobut-2-enoate Derivatives as Novel Covalent Pin1 Inhibitors with Antitumor Activity. J Med Chem. 2026 Jul 2.
[Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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