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Cat. No.: HY-181973

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WDR5 ligand 3

WDR5 ligand 3 is a WDR5 ligand that can be used for the synthesis of PORTACs, such as PROTAC WDR5 degrader 2 (HY-181972).

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Formule: C₃₄H₃₆F₄N₆O₃
Masse moléculaire:652.68

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

WDR5 ligand 3 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

WDR5 ligand 3 is a WDR5 ligand that can be used for the synthesis of PORTACs, such as PROTAC WDR5 degrader 2 (HY-181972)^[1].

Chemical Information

Masse moléculaire 652.68
Formule C₃₄H₃₆F₄N₆O₃
SMILES

C#CCN1CCN(CC1)C(C2=CC=C(C(C3=CC(NC(C(C(C(F)(F)F)=C4)=CNC4=O)=O)=C(N5C[C@@H](N([C@@H](C5)C)C)C)C=C3)=C2)F)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Lu H, et al. Design, Synthesis and Biological Evaluation of Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors. J Med Chem. 2025;68(23):25011-25025. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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