MX2 Antibody
(Synonyms: Interferon-induced GTP-binding protein Mx2, Interferon-regulated resistance GTP-binding protein MxB, Myxovirus resistance protein 2, p78-related protein, MX2)MX2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to MX2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
MX2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to MX2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 82 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 82 kDa
Synthetic peptide corresponding to the center region of human MX2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MX2 is an Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression
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Subcellular Localization
Cytoplasm; Nucleus; Nucleus, nuclear pore complex
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Expression
Induction: By type I and type III interferons. -
Isoforms & Post-Translational Modification
MX2 has 2 isoforms, P20592-1: amino acid length is 715, molecular weight is 82089 Da (predicted); P20592-2: amino acid length is 201, molecular weight is 22105 Da (predicted).MX2 存在 2 个异构体，P20592-1：氨基酸个数为 715 个，分子量为 82089 Da (预测)；P20592-2：氨基酸个数为 201 个，分子量为 22105 Da (预测)。
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SwissProt ID
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Synonyms
Interferon-induced GTP-binding protein Mx2, Interferon-regulated resistance GTP-binding protein MxB, Myxovirus resistance protein 2, p78-related protein, MX2
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