Tec - tec protein tyrosine kinase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21682

Summary

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; peptidyl-tyrosine autophosphorylation; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to act upstream of or within immune system process and phosphorylation. Located in cell-cell junction. Is expressed in several structures, including central nervous system; extraembryonic component; placenta; retina; and spleen. Orthologous to human TEC (tec protein tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Tec Products (4)

mRNA Protein Name
NM_001113460.2 NP_001106931.1 tyrosine-protein kinase Tec isoform a
NM_001113461.2 NP_001106932.1 tyrosine-protein kinase Tec isoform b
NM_001113464.2 NP_001106935.1 tyrosine-protein kinase Tec isoform a
NM_013689.5 NP_038717.2 tyrosine-protein kinase Tec isoform c

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11716489 MGI
Cellular Component GO Annotation Evidence References Source
located in cell-cell junction IDA
IDA: Inferred from direct assay
23793062 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein kinase Tec

  • cytoplasmic tyrosine kinase, Dscr28C related

  • protein tyrosine kinase TecI

  • protein tyrosine kinase TecIIA

  • protein tyrosine kinase TecIIB

  • protein tyrosine kinase TecIII

  • protein tyrosine kinase TecIV

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (23)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130665 TL12-186 Inhibitor 99.23% Unkown
HY-80002 BMX-IN-1 Inhibitor 99.04% Unkown
HY-18010 PCI 29732 Inhibitor 99.59% Unkown
HY-149051 BGB-8035 Inhibitor 99.00% Unkown
HY-176071 TEC 4 Degrader 99.57% Unkown
HY-109143B (R)-Elsubrutinib Inhibitor 98.0% Unkown
HY-N11772 Mutanocyclin Inhibitor 99.94% Unkown
HY-111781 Civorebrutinib Inhibitor / Unkown
HY-174129 TM471-1 / Unkown
HY-117900 PF-06250112 Inhibitor / Unkown
HY-145373 BMS-986143 Inhibitor / Unkown
HY-111289 Tec-IN-14 Inhibitor / Unkown
HY-117900A (Rac)-PF-06250112 / Unkown
HY-123541 Tec-IN-6 Inhibitor / Unkown
HY-124827 Tec-IN-1 Inhibitor / Unkown
HY-142932 BTK-IN-6 Inhibitor / Unkown
HY-172432 Plodicitinib Inhibitor / Unkown
HY-174999 JAK3-IN-18 Inhibitor / Unkown
HY-E70833 ITK Recombinant Human Active Protein Kinase / Unkown
HY-RS14346 TEC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17530 Tec Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18292 Nr4a3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23986 Tec Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tec NCBI NCBI:7006