PF-06250112
PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC50s of 0.9 nM and 1.2 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1609465-89-5
- Formula: C22H20F2N6O2
- Molecular Weight:438.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.5 nM (BTK), 0.9 nM (BMX), 1.2 nM (TEC)[1]
Chemical Information
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CAS No. 1609465-89-5
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Molecular Weight 438.43
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Formula C22H20F2N6O2
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SMILES
O=C(N)C1=C(N(N=C1C2=CC=C(C=C2)OC3=CC=C(C=C3F)F)[C@@H]4CN(CCC4)C#N)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PF-06250112 Related Classifications
HY-117900 Related Classifications
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