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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
DBT
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "DBT" in MCE Product Catalog:
2
Target:
Research Areas:
Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir (ABI-H0731) suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s from 1.84 μM to 7.3 μM .
Research Areas:
Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with a Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .
Cat. No.: HY-156746
DBt-10 is a PROTAC degrader that targets and degrades BTK by recruiting DCAF1. It degrades BTK in TMD8 BTK-GFP/mCherry cells with a DC50 of 137 nM. DBt-10 induces CRL4 DCAF1-dependent ubiquitination and proteasomal degradation of BTK, and retains BTK-degrading and antiproliferative activities in TMD8 cells that are resistant to CRBN-BTK PROTACs due to loss of CRBN expression. DBt-10 has a high survival window and exhibits extremely weak apoptosis-inducing effects on lymphoma cells. DBt-10 can be used for research on diffuse large B-cell lymphoma .
Cat. No.: HY-RS17320
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Dbt Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dbt gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23775
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Dbt Rat Pre-designed siRNA Set A contains three designed siRNAs for Dbt gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Research Areas:
Dibenzothiophene (Standard) is the analytical standard of Dibenzothiophene (HY-B0973). This product is intended for research and analytical applications. Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .
Cat. No.: HY-RS03554
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DBT Human Pre-designed siRNA Set A contains three designed siRNAs for DBT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P74207
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DBT; Dihydrolipoamide Branched Chain Transacylase (E2 Component Of Branched Chain Keto Acid Dehydrogenase Complex; Maple Syrup Urine Disease); Dihydrolipoamide Branched Chain Transacylase E2; Lipoamide Acyltransferase Component Of Mitochondrial Branched-C
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Cat. No.: HY-109195R
CAS No.: 2090064-66-5
Synonyms: ABI-H0731 (Standard)
Target:
Research Areas:
Vebicorvir (Standard) is the analytical standard of Vebicorvir (HY-109195). This product is intended for research and analytical applications. Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir (ABI-H0731) suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s from 1.84 μM to 7.3 μM .
Cat. No.: HY-P705796
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CSNK1E; Non-Specific Serine/Threonine Protein Kinase; Casein Kinase 1 Epsilon; Alternative Protein CSNK1E; CKIepsilon; Casein Kinase 1, Epsilon; HCKIE; CKI-Epsilon; CKIE; CKIe; Casein Kinase I Isoform Epsilon
Species:
Source:
Cat. No.: HY-P72152
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSNK1E; Non-Specific Serine/Threonine Protein Kinase; Casein Kinase 1 Epsilon; Alternative Protein CSNK1E; CKIepsilon; Casein Kinase 1, Epsilon; HCKIE; CKI-Epsilon; CKIE; CKIe; Casein Kinase I Isoform Epsilon
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
