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DBT Antibody (YA8534)(PBS only)

(Synonyms: BCATE2; BCKAD-E2; BCKADE2; BCOADC-E2; E2; E2B)

DBT Antibody (YA8534) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DBT.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • DBT Antibody (YA8534)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:100-250 1:100

Product Details

Description

DBT Antibody (YA8534) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DBT.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 46.4 kDa
Immunogen

Full length human recombinant protein of human DBT produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    DBT is a The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component

  • Subcellular Localization

    Mitochondrion matrix

  • Isoforms & Post-Translational Modification

    P11182: 482 amino acids, molecular weight 53517 Da.

  • Subunit

    Forms a 24-polypeptide structural core with octahedral symmetry that represents the E2 component of the branched-chain alpha-ketoacid dehydrogenase (BCKDH) complex

  • SwissProt ID

    P11182

  • Synonyms

    BCATE2; BCKAD-E2; BCKADE2; BCOADC-E2; E2; E2B

DBT Antibody (YA8534)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • DBT Antibody (YA8534)(PBS only) Product Image