47 Results for "

Hops

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "Hops" in MCE Product Catalog:

16
Xanthohumol
Xanthohumol
0 Images
16 Publications Verification
Cat. No.: HY-N1067
CAS No.: 6754-58-1
Category:  

Infection Flavonoids Chalcones Humulus lupulus L. Phenols Polyphenols Plants Moraceae Disease Research Fields

Target:  

COX Acyltransferase Apoptosis HSV CMV Influenza Virus

Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
4
Isoxanthohumol
Isoxanthohumol
0 Images
4 Cited Publications
Cat. No.: HY-N2584A
CAS No.: 521-48-2
Category:  

Infection Flavonoids Anti-aging Humulus lupulus L. Flavonones Plants Moraceae Disease Research Fields Cancer

Target:  

HSV Apoptosis Reactive Oxygen Species (ROS) Autophagy CMV Fungal Integrin S100 Protein

Isoxanthohumol is an orally active flavonoid compound. Isoxanthohumol has biological activities such as anti-tumor, anti-inflammatory, antioxidant, antiviral, antifungal, and inhibition of adipogenesis. Isoxanthohumol can induce apoptosis, autophagy, and migration of tumor cells. Isoxanthohumol is active against viruses such as HSV, BVDV, CMV, and Rhino. Isoxanthohumol can be used for the research of tumors, metabolic, and inflammatory diseases .
1
8-​Prenylnaringenin
8-​Prenylnaringenin
0 Images
1 Cited Publications
Cat. No.: HY-N2787
CAS No.: 53846-50-7
Category:  

Flavonoids Humulus lupulus L. Flavonones Phenols Polyphenols Plants Moraceae Disease Research Fields Cancer

Target:  

PI3K Akt AMPK Sirtuin Reactive Oxygen Species (ROS) SOD

8-Prenylnaringenin is an orally active prenyl flavonoid. 8-Prenylnaringenin can be isolated from the hop spike Humulus lupulus. 8-Prenylnaringenin activates the PI3K/Akt pathway and the AMPK pathway, upregulates OXPHOS complexes (II, III, and V) and Sirt1, and reduces ROS production and SOD activity. 8-Prenylnaringenin improves muscle atrophy and obesity and inhibits angiogenesis. 8-Prenylnaringenin exhibits anticancer activity against glioblastoma and colon cancer. 8-Prenylnaringenin also has LH/FSH regulatory activity. 8-prenylnaringenin may be used in bone health research .
1
Desmethylxanthohumol
Desmethylxanthohumol
0 Images
1 Cited Publications
Cat. No.: HY-122966
CAS No.: 115063-39-3
Purity:  99.66%
Category:  

Flavonoids Chalcones Humulus lupulus L. Phenols Polyphenols Plants Moraceae Disease Research Fields Cancer

Target:  

Apoptosis

Desmethylxanthohumol is a prenylated hydroxychalcone isolated from hop cones (Humulus lupulus L.). Desmethylxanthohumol is a powerful apoptosis inducing agent. Desmethylxanthohumol has antiplasmodial, antiproliferative, and antioxidant bioactivities .
1
Xanthohumol C
Xanthohumol C
0 Images
1 Cited Publications
Cat. No.: HY-N11769
CAS No.: 189299-05-6
Category:  

Humulus lupulus L. Phenols Polyphenols Plants Moraceae

Target:  

Bacterial

Xanthohumol C is a prenylchalcone, that can be isolated from the hops of Humulus lupulus .
1
Xanthohumol D
Xanthohumol D
0 Images
1 Cited Publications
Cat. No.: HY-N1066
CAS No.: 274675-25-1
Category:  

Flavonoids Chalcones Humulus lupulus L. Phenols Polyphenols Plants Moraceae Disease Research Fields Cancer

Target:  

Others

Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro .
(E/Z)-Polydatin
(E/Z)-Polydatin
0 Images
Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
Category:  

Stilbenes Polygonaceae Reynoutria japonica Houtt. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Drug Isomer

(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products and chocolate products. Polydatin exhibits multiple biological properties, such as anti-platelet aggregation, anti-low-density lipoprotein oxidation, cardioprotective activity, anti-inflammatory and immunomodulatory functions. Polydatin shows favorable cytotoxic effects against various tumor cell lines, including cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells .
(2S)-Isoxanthohumol
(2S)-Isoxanthohumol
0 Images
Cat. No.: HY-N2584
CAS No.: 70872-29-6
Category:  

Flavonoids Humulus lupulus L. Flavonones Phenols Polyphenols Plants Moraceae Disease Research Fields Cancer

Target:  

Others

(2S)-Isoxanthohumol is a microbial biotransformed metabolite of the hop prenylflavanone Isoxanthohumol .
Lupulone
Lupulone
0 Images
Cat. No.: HY-124923
CAS No.: 468-28-0
Purity:  ≥99.0%
Category:  

Infection Humulus lupulus L. Ketones, Aldehydes, Acids Plants Moraceae Disease Research Fields Cancer

Target:  

Bacterial

Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties .
3-Methyl-2-butenal
3-Methyl-2-butenal
0 Images
Cat. No.: HY-34409
CAS No.: 107-86-8
Synonyms: 3-Methylbut-2-en-1-al
Category:  

Natural Products Humulus lupulus L. Plants Moraceae

Target:  

Drug Intermediate

3-Methyl-2-butenal (3-Methylbut-2-en-1-al) is an enone aldehyde that occurs in hops (Humulus lupulus L.) .
2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid
2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid
0 Images
Cat. No.: HY-N10668
CAS No.: 57061-17-3
Category:  

Alkaloids Humulus lupulus L. Plants Moraceae Indole Alkaloids

Target:  

Others

2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid (compound 29) is a natural polyphenol compound found in hop bract .
DMBP
DMBP
0 Images
Cat. No.: HY-177120
CAS No.: 133156-42-0
Target:  

Autophagy

Research Areas:  

Cancer

DMBP is a VPS41 inhibitor. DMBP induces methuosis and inhibits autophagy in cancer cells. DMBP inhibits the fusion of late endosomes and autophagosomes with lysosomes. DMBP effectively inhibits metastasis in a mouse metastatic melanoma model. DMBP can be used for the study of melanoma .
Xanthohumol I
Xanthohumol I
0 Images
Cat. No.: HY-N10917
CAS No.: 688360-06-7
Category:  

Humulus lupulus L. Phenols Polyphenols Plants Moraceae

Target:  

Drug Derivative

Xanthohumol I is a derivative of Chalcone (HY-121054) that can be isolated from Humulus lupulus L. (hops). Xanthohumol I exhibits free radical scavenging activity .
mGluR2 modulator 1
mGluR2 modulator 1
0 Images
Cat. No.: HY-130630
CAS No.: 2671063-84-4
Purity:  ≥98.0%
Target:  

mGluR

Research Areas:  

Neurological Disease

mGluR2 modulator 1 (compound 95) is a potent and BBB-penetrated mGluR2 (metabotropic glutamate receptor-2) positive allosteric modulator, with an EC50 of 0.03 μM. mGluR2 modulator 1 can be used for psychosis research .
ALPL Human Pre-designed siRNA Set A
ALPL Human Pre-designed siRNA Set A
Cat. No.: HY-RS00632
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

ALPL Human Pre-designed siRNA Set A contains three designed siRNAs for ALPL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Camphorsulfonate sodium
Camphorsulfonate sodium
0 Images
Cat. No.: HY-W272811
CAS No.: 34850-66-3
Target:  

Drug Intermediate Fungal

Research Areas:  

Infection

Camphorsulfonate sodium is an organic synthesis intermediate. Camphorsulfonate sodium can be used for synthesis of derivatives with SDH inhibitory activity through scaffold hopping. Camphorsulfonate sodium is also an organocatalyst that can be used as a pore-forming additive for modulating the porosity of the graphene film. Camphorsulfonate sodium can be used for binder-free porous graphene film and fungicide research .
Hops Flower Extract
Hops Flower Extract
0 Images
Cat. No.: HY-N13225
Category:  

Infection Neurological Disease Plants Disease Research Fields

Target:  

Others

Hops Flower Extract is the extract of Hops Flower.
Xanthohumol (Standard)
Xanthohumol (Standard)
0 Images
Cat. No.: HY-N1067R
CAS No.: 6754-58-1
Category:  

Flavonoids Chalcones Humulus lupulus L. Phenols Polyphenols Plants Moraceae

Target:  

Reference Standards COX Acyltransferase Apoptosis HSV CMV Influenza Virus

Xanthohumol (Standard) is the analytical standard of Xanthohumol. This product is intended for research and analytical applications. Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
Hulupinic acid
Hulupinic acid
0 Images
Cat. No.: HY-N9140
CAS No.: 1891-42-5
Category:  

Natural Products Humulus lupulus L. Plants Moraceae

Target:  

Others

Hulupinic acid is a prominent oxidation product of hop acids .
Tetrasul
Tetrasul
0 Images
Cat. No.: HY-124901
CAS No.: 2227-13-6
Target:  

Parasite

Research Areas:  

Infection

Tetrasul is an acaricide. Tetrasul inhibits Tetranychus urticae and aphids on hops. Tetrasul has also been used in research of erythematous (type one) rosacea .
Assay Types