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Cat. No.: HY-W744577

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Dexamethasone acetate-d₅

(Synonyms: Dexamethasone 21-acetate-d₅; Hexadecadrol acetate-d₅)

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Dexamethasone acetate-d₅ (Dexamethasone 21-acetate-d₅; Hexadecadrol acetate-d₅) is the deuterium labeled Dexamethasone acetate (HY-14648A). Dexamethasone acetate (Dexamethasone 21-acetate) is the acetate form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone acetate has a longer duration of action than Dexamethasone. Dexamethasone acetate can accumulate at inflammatory sites, in mouse liver and mouse lung via nanostructured lipid carriers. Dexamethasone acetate can be used to prepare topical formulations for studies related to sensorineural hearing loss, γ-carrageenan-induced paw edema, chronic active hepatitis, pulmonary diseases, and inflammation after vitreoretinal surgery.

For research use only. We do not sell to patients.

Formula: C₂₄H₂₆D₅FO₆
Molecular Weight:439.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (251 KB)

Dexamethasone acetate-d₅ Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
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Bioz

Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 1177-87-3
Molecular Weight 439.53
Formula C₂₄H₂₆D₅FO₆
SMILES

O=C1C=C[C@]2(C(C([2H])(C[C@@]3([C@@]2([C@H](C[C@]4([C@]3(C[C@H]([C@@]4(C(C([2H])(OC(C)=O)[2H])=O)O)C)[H])C)O)F)[H])[2H])=C1[2H])C
Synonyms

Dexamethasone 21-acetate-d₅; Hexadecadrol acetate-d₅
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.