Dux4 - double homeobox 4 Gene

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including negative regulation of G0 to G1 transition; negative regulation of cell population proliferation; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of T cell differentiation. Predicted to be located in Golgi apparatus; cytosol; and nucleus. Predicted to be active in nucleus. Orthologous to several human genes including DUX4L1 (double homeobox 4 like 1 (pseudogene)); DUX4L2 (double homeobox 4 like 2 (pseudogene)); and DUX4L4 (double homeobox 4 like 4 (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]