Casein kinase 1δ-IN-27
Casein kinase 1δ-IN-27 (Compound 8) is the inhibitor for casein kinase 1 that inhibits CK1α, CK1δ, CK1ε, and p38α with IC50s of 22, 16.5, 9.41 and 14.8 nM, respectively. Casein kinase 1δ-IN-27 inhibits the DUX4 expression with an IC50 of 10 nM.
For research use only. We do not sell to patients.
- CAS No.: 1095706-65-2
- Formula: C21H19FN6
- Molecular Weight:374.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CK1ε 9.41 nM (IC50) |
p38α 14.8 nM (IC50) |
CK1γ2 16.5 nM (IC50) |
CK1α 22 nM (IC50) |
Chemical Information
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CAS No. 1095706-65-2
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Molecular Weight 374.41
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Formula C21H19FN6
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SMILES
FC1=CC=C(C2=C(C3=CC=NC=C3)N4N=C(N5CCNCC5)C=CC4=N2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)