1095706-65-2
1095706-65-2
Chemical Structure
Casein kinase 1δ-IN-27
- CAS No.: 1095706-65-2
- Formula:C21H19FN6
- Molecular Weight:374.41
SMILES: FC1=CC=C(C2=C(C3=CC=NC=C3)N4N=C(N5CCNCC5)C=CC4=N2)C=C1
Biological Activity: Casein kinase 1δ-IN-27 (Compound 8) is the inhibitor for casein kinase 1 that inhibits CK1α, CK1δ, CK1ε, and p38α with IC50s of 22, 16.5, 9.41 and 14.8 nM, respectively. Casein kinase 1δ-IN-27 inhibits the DUX4 expression with an IC50 of 10 nM[1].
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Casein kinase 1δ-IN-27 | Casein kinase 1δ-IN-27 (Compound 8) is the inhibitor for casein kinase 1 that inhibits CK1α, CK1δ, CK1ε, and p38α with IC50s of 22, 16.5, 9.41 and 14.8 nM, respectively. Casein kinase 1δ-IN-27 inhibits the DUX4 expression with an IC50 of 10 nM. | |||||||||||||||||||||
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