Lyso Flipper-TR 29
Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form.
For research use only. We do not sell to patients.
- CAS No.: 2324152-35-2
- Formula: C35H37N5O4S6
- Molecular Weight:784.09
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Lyso Flipper-TR 29 enters lysosomes by transient deprotonation to diffuse in neutral form across the hydrophobic membrane, while its return to the cytosol is not possible because low pH≈5 within lysosomes prevents transient deprotonation. Lyso Flipper-TR 29 tracks also late endosomes, but fails to label early endosomes (EE) because their internal pH >6 is too high to prevent transient deprotonation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2324152-35-2
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Molecular Weight 784.09
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Formula C35H37N5O4S6
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SMILES
CC1=C(C#N)SC(C2=C3C(C)=C(C4=C(C)C(SC5=C6SC(COCC7=CN(CCCCCCN8CCOCC8)N=N7)=C5C)=C6S4)S2)=C1S3(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lyso Flipper-TR 29 Related Classifications
HY-D2321 Related Classifications
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