4 Results for "

human FSHR

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "human FSHR" in MCE Product Catalog:

Cat. No.: HY-RS05124
Research Areas:  

Others

FSHR Human Pre-designed siRNA Set A contains three designed siRNAs for FSHR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-182705
CAS No.: 914093-78-0
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

Org 214444-0 is an orally active, nanomolar-potent and selective FSHR agonist, with EC50 values of 2.0 nM and 1.2 nM in human and rat (measured in CHO cells). Org 214444-0 activates human granulosa cells in vitro, supports rat follicular development and induces ovulation in vivo. Org 214444-0 can be used for the research of infertility .
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Cat. No.: HY-P72198
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FSHR; FSHRO; Prev. ODG1; FSH Receptor; LGR1; FSHR1; Follicle-Stimulating Hormone Receptor; FSH-R; Follitropin Receptor; Follicle Stimulating Hormone Receptor; LRRNT Domain-Containing Protein
Species:  
Source:  
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Cat. No.: HY-W673613
CAS No.: 1067191-08-5
Research Areas:  

Endocrinology

ADX68692 is an orally active FSHR negative allosteric regulator, with an IC50 value of 140 nM against hFSHR. ADX68692 antagonizes hCG (HY-107953)-mediated cAMP production, β-arrestin 2 recruitment, and the LH/CGR signaling pathway. ADX68692 partially inhibits testosterone synthesis. ADX68692 blocks follicle growth, disrupts the estrous cycle in rats, and reduces the pregnancy rate in rats. ADX68692 can be used in research related to contraception and endometriosis .
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