914093-78-0
914093-78-0
Chemical Structure
Org 214444-0
- CAS No.: 914093-78-0
- Formula:C30H32BrF2N3O5S
- Molecular Weight:664.56
InChIKey: HZUASZIVIBUGHW-YMGMXPECSA-N
SMILES: N#CC1=C(C)NC(C[C@@H](CC2=O)CCC)=C2[C@@H]1C3=CC(OCC)=C(C(Br)=C3)OCC4=C(C=C(C(F)=C4)F)NS(C)(=O)=O
Biological Activity: Org 214444-0 is an orally active, nanomolar-potent and selective FSHR agonist, with EC50 values of 2.0 nM and 1.2 nM in human and rat (measured in CHO cells). Org 214444-0 activates human granulosa cells in vitro, supports rat follicular development and induces ovulation in vivo. Org 214444-0 can be used for the research of infertility[1].
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Org 214444-0 | Org 214444-0 is an orally active, nanomolar-potent and selective FSHR agonist, with EC50 values of 2.0 nM and 1.2 nM in human and rat (measured in CHO cells). Org 214444-0 activates human granulosa cells in vitro, supports rat follicular development and induces ovulation in vivo. Org 214444-0 can be used for the research of infertility. | |||||||||||||||||||||
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References
Keywords
