Ectoine
Based on 1 Customer Validation
Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis.
For research use only. We do not sell to patients.
- Purity: 99.87%
- CAS No.: 96702-03-3
- Formula: C6H10N2O2
- Molecular Weight:142.16
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Bacterial[1]
Ectoine (0-5% (w/v); 0-24 h; human erythrocytes) protects the cells from damage caused by SDS treatment[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 96702-03-3
-
Appearance Solid
-
Molecular Weight 142.16
-
Formula C6H10N2O2
-
Color White to off-white
-
SMILES
O=C([C@H]1NC(C)=NCC1)O
-
Structure Classification
-
Initial Source
Ethtothiorhodospiru halochloris、Ehalonas elongata
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
H2O : ≥ 200 mg/mL (1406.89 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (703.44 mM); Clear solution; Need ultrasonic
Purity & Documentation
-
Data Sheet (270 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.0344 mL | 35.1721 mL | 70.3443 mL | 175.8607 mL |
| 5 mM | 1.4069 mL | 7.0344 mL | 14.0689 mL | 35.1721 mL | |
| 10 mM | 0.7034 mL | 3.5172 mL | 7.0344 mL | 17.5861 mL | |
| 15 mM | 0.4690 mL | 2.3448 mL | 4.6896 mL | 11.7240 mL | |
| 20 mM | 0.3517 mL | 1.7586 mL | 3.5172 mL | 8.7930 mL | |
| 25 mM | 0.2814 mL | 1.4069 mL | 2.8138 mL | 7.0344 mL | |
| 30 mM | 0.2345 mL | 1.1724 mL | 2.3448 mL | 5.8620 mL | |
| 40 mM | 0.1759 mL | 0.8793 mL | 1.7586 mL | 4.3965 mL | |
| 50 mM | 0.1407 mL | 0.7034 mL | 1.4069 mL | 3.5172 mL | |
| 60 mM | 0.1172 mL | 0.5862 mL | 1.1724 mL | 2.9310 mL | |
| 80 mM | 0.0879 mL | 0.4397 mL | 0.8793 mL | 2.1983 mL | |
| 100 mM | 0.0703 mL | 0.3517 mL | 0.7034 mL | 1.7586 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.