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Cat. No.: HY-151352

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DHDPS-IN-1

DHDPS-IN-1 (compound 8) is a DHDPS inhibitor (IC₅₀: 39 μM). DHDPS-IN-1 can be used in the area of antibacterial and herbicidal.

For research use only. We do not sell to patients.

CAS No.: 1233344-34-7
Formula: C₁₃H₁₁NO₅S
Molecular Weight:293.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

DHDPS-IN-1 Chemical Structure

CAS No.: 1233344-34-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

DHDPS-IN-1 (compound 8) is a DHDPS inhibitor (IC₅₀: 39 μM). DHDPS-IN-1 can be used in the area of antibacterial and herbicidal^[1].

IC₅₀ & Target

DHDPS^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>500 μM Compound: 6h	Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34826680]
HepG2	EC₅₀	>500 μM Compound: 6h	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34826680]

Chemical Information

CAS No. 1233344-34-7
Molecular Weight 293.30
Formula C₁₃H₁₁NO₅S
SMILES

COC1=CC=C(C=C1)/C=C2SC(N(C\2=O)CC(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rebecca M Christoff, et al. Synthesis and structure-activity relationship studies of 2,4-thiazolidinediones and analogous heterocycles as inhibitors of dihydrodipicolinate synthase. Bioorg Med Chem. 2021 Dec 15;52:116518. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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