Zolertine
Zolertine is an α-adrenergic receptor antagonist, with a pKi of 6.35 for rabbit α1A-adrenergic receptor and a pKi of 6.81 for rat α1B-adrenergic receptor. Zolertine competitively blocks α1D-adrenergic receptor-mediated vasoconstriction and α1A-adrenergic receptor-mediated vasoconstriction in arteries. Zolertine can be used in the research of hypertension.
For research use only. We do not sell to patients.
- CAS No.: 4004-94-8
- Formula: C13H18N6
- Molecular Weight:258.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
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Biological Activity
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α1A-adrenergic receptor 6.35 (pKi) |
α1B-adrenergic receptor 6.81 (pKi) |
Zolertine (30 min) competes for the α1-adrenergic receptor binding sites on rat liver (α1B) and rabbit liver (α1A) cell membranes, with pKi values of 6.81 and 6.35, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4004-94-8
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Molecular Weight 258.32
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Formula C13H18N6
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SMILES
C1(CCN2CCN(CC2)C3=CC=CC=C3)=NN=NN1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Zolertine Related Classifications
HY-183177 Related Classifications
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