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Referencia número: HY-N20709

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Euchrenone B1

Euchrenone B1 is a flavonoid. Euchrenone B1 can be isolated from the stem bark of Maackia amurensis and the roots of Euchresta formosana. Euchrenone B1 exhibits anticancer activity against cervical cancer, melanoma, breast cancer, and liver cancer.

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No. CAS: 119061-09-5
Fòrmula: C₃₀H₃₄O₅
Peso molecular:474.60

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Euchrenone B1 Chemical Structure

No. CAS: 119061-09-5

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Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

In Vitro

Euchrenone B1 (48 h) potently inhibits the growth of HeLa, A375S2, MCF-7, and HepG2 human cancer cell lines in vitro, with the highest potency against HeLa cells (IC₅₀ = 4.5 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

A375S2, HeLa, MCF-7, HepG2
Concentration:

Various concentrations
Incubation Time:

48 h
Result:

Exhibited dose-dependent cytotoxicity against all four tested human cancer cell lines, with IC₅₀ values of 14.8 μM for A375S2, 4.5 μM for HeLa, 13.1 μM for MCF-7, and 32.9 μM for HepG2.
Showed the most potent cytotoxicity against the HeLa cell line among all tested compounds.

Chemical Information

No. CAS 119061-09-5
Peso molecular 474.60
Fòrmula C₃₀H₃₄O₅
SMILES

O=C1C(=COC2=C1C(O)=C(C(O)=C2CC=C(C)C)CC=C(C)C)C=3C=CC(O)=C(C3)CC=C(C)C
Structure Classification
- Flavonoids
- Isoflavones
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Li X, et al. Cytotoxic prenylated flavonoids from the stem bark of Maackia amurensis. Chemical & pharmaceutical bulletin. 2009 Mar;57(3):302-6. [Content Brief]

[2]. Lo W L, et al. The constituents of Euchresta formosana[J]. Journal of the Chinese Chemical Society, 2002, 49(3): 421-426.

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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