L-736380
L-736380 is a high affinity CCK-B (cholecystokinin B receptor) receptor antagonist, with IC50 values of 0.054 nM and 400 nM for CCK-B and CCK-A, respectively. L-736380 dose-dependently inhibits gastric acid secretion in anesthetized rats (ID50, 0.064 mg/kg) and ex vivo binding of [125I]CCK-8S in BKTO mice brain membranes (ED50, 1.7 mg/kg).
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- No. CAS: 152885-49-9
- Fòrmula: C25H29N9O2
- Peso molecular:487.56
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
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No. CAS 152885-49-9
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Peso molecular 487.56
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Fòrmula C25H29N9O2
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SMILES
O=C(N[C@H]1C(N(C2=CC=CC=C2C(C3CCCCC3)=N1)C)=O)NC4=CC=CC(N(C5=NNN=N5)C)=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)