2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Fasobegron

Fasobegron is a β3-adrenergic receptor agonist with a human EC50 of 4.8 nM. Fasobegron shows an EC50 of 250 nM for human β1-adrenergic receptors. Fasobegron can be used for the research of overactive bladder.

For research use only. We do not sell to patients.

Fasobegron

Fasobegron Chemical Structure

CAS No. : 643094-49-9

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Fasobegron Related Antibodies

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Description

Fasobegron is a β3-adrenergic receptor agonist with a human EC50 of 4.8 nM. Fasobegron shows an EC50 of 250 nM for human β1-adrenergic receptors. Fasobegron can be used for the research of overactive bladder[1].

IC50 & Target[1]

β3 adrenoceptor

4.8 nM (EC50)

β1 adrenoceptor

250 nM (EC50)

In Vitro

Fasobegron (Compound 1a) potently and selectively activates human β3-ARs in CHO cells, with an EC50 of 4.8 nM, and exhibits >2000-fold selectivity over human β2-ARs (EC50 >10000 nM) and ~52-fold selectivity over human β1-ARs (EC50 = 250 nM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fasobegron Related Antibodies
Molecular Weight

425.91

Formula

C24H24ClNO4
CAS No.
SMILES

O(C)C=1C=C(C=CC1C(O)=O)C2=CC=C(CCNC[C@H](O)C3=CC(Cl)=CC=C3)C=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Fasobegron Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fasobegron643094-49-9Adrenergic ReceptorBeta Receptoroveractive bladderCHO cellsInhibitorinhibitorinhibit

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