Direct red 254
Based on 1 Customer Validation
Direct Red 254 is a bisazo dye for textile applications. Direct Red 254 can be used for amyloid tissue staining in basic research on neurodegenerative diseases (e.g., Alzheimer's disease).
For research use only. We do not sell to patients.
- CAS No.: 6300-50-1
- Formula: C22H15N5Na2O7S2
- Molecular Weight:571.49
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Direct Red 254 (1% (w/v)) stains amyloid-like synthetic peptides and induces birefringence in vitro: some peptide fragments with amyloid-like properties (e.g., peptide fragment N14) exhibit green birefringence under polarized light after staining. This is a typical characteristic of amyloid deposits[1].
Direct Red 254 can be effectively biodecolorized, and its decolorization efficiency is affected by its molecular structure and aggregation behavior in aqueous solution[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6300-50-1
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Appearance Solid
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Molecular Weight 571.49
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Formula C22H15N5Na2O7S2
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Color black
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SMILES
O=S(C1=C(N=NC2=CC=C(N=NC3=CC=C(S(=O)(O[Na])=O)C=C3)C=C2)C(O)=C4C=CC(N)=CC4=C1)(O[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Hilbich C, et al. Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11. J Biol Chem. 1993;268(35):26571-26577. [Content Brief]
[2]. Brás R, et al. Monoazo and diazo dye decolourisation studies in a methanogenic UASB reactor. J Biotechnol. 2005;115(1):57-66. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Direct red 254 Related Classifications
HY-D0404 Related Classifications
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