Zankiren
Zankiren (A-72517) is an orally active inhibitor for renin. Zankiren exhibits renal vasodilator effect, through reduction of angiotensin II formation without affecting other vasodilator mechanisms.
For research use only. We do not sell to patients.
- CAS No.: 138742-43-5
- Formula: C35H55N5O6S2
- Molecular Weight:705.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 138742-43-5
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Molecular Weight 705.97
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Formula C35H55N5O6S2
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SMILES
CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC([C@H](CC2=CSC=N2)NC([C@@H](CS(=O)(N3CCN(CC3)C)=O)CC4=CC=CC=C4)=O)=O
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Synonyms
A-72517
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wessale JL, Kleinert HD, Calzadilla SV, Kovar PJ, Rosenberg SH.Effects of renin inhibitor A-72517 on hemodynamics and cardiac function in sodium-depleted dogs.Am J Hypertens. 1993 Jun;6(6 Pt 1):514-21. [Content Brief]
[2]. Fisher ND, et al., Renal vascular responses to renin inhibition with zankiren in men. Clin Pharmacol Ther. 1995 Mar;57(3):342-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)