Losoxantrone hydrochloride
Losoxantrone hydrochloride (CI 941 hydrochloride) is a DNA-binding agent. Losoxantrone hydrochloride has broad-spectrum antitumour activity. Losoxantrone hydrochloride induces dose-dependent leukopenia.
For research use only. We do not sell to patients.
- CAS No.: 88303-61-1
- Formula: C22H29Cl2N5O4
- Molecular Weight:498.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LoVo | IC50 |
0.053 μg/mL
Compound: DuP-941
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In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.
In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.
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[PMID: 9876113] |
| LoVo | IC50 |
44.5 μg/mL
Compound: DuP-941
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In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.
In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.
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[PMID: 9876113] |
Chemical Information
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CAS No. 88303-61-1
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Molecular Weight 498.40
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Formula C22H29Cl2N5O4
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SMILES
OCCNCCNC1=C2C3=C(C=C1)N(CCNCCO)N=C3C4=C(C(O)=CC=C4)C2=O.Cl.Cl
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Synonyms
CI 941 hydrochloride; DUP 94 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Losoxantrone hydrochloride Related Classifications
HY-106091B Related Classifications
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