25 Results for "

cryptosporidium

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "cryptosporidium" in MCE Product Catalog:

9
Triacsin C
Triacsin C
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9 Publications Verification
Cat. No.: HY-N6707
CAS No.: 76896-80-5
Synonyms: WS 1228A; FR 900190
Category:  

Infection Microorganisms Ketones, Aldehydes, Acids Disease Research Fields

Target:  

ACSL Family Parasite

Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .
2
Broxyquinoline
Broxyquinoline
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2 Cited Publications
Cat. No.: HY-B1212
CAS No.: 521-74-4
Synonyms: Dibromohydroxyquinoline; 5,7-Dibromo-8-hydroxyquinoline
Target:  

Parasite Influenza Virus

Research Areas:  

Infection

Broxyquinoline (Dibromohydroxyquinoline) is an effective inhibitor of severe fever with thrombocytopenia syndrome virus (SFTSV) with an IC50 of 5.8 µM. Additionally, Broxyquinoline is an inhibitor of CpACBP1 with an IC50 of 64.9 μM. CpACBP1 is a fatty acyl-CoA binding protein of Cryptosporidium parvum, thus Broxyquinoline has the potential to inhibit parasite growth. Broxyquinoline shows promise for research in the field of infectious diseases .
1
LysRs-IN-2
LysRs-IN-2
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1 Cited Publications
Cat. No.: HY-126130
CAS No.: 2170696-76-9
Purity:  99.92%
Target:  

Aminoacyl-tRNA Synthetase

Research Areas:  

Infection

LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0.015 μM and 0.13 μM for Plasmodium falciparum lysyl-tRNA synthetase (PfKRS) and Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS), respectively .
1
EDI048
EDI048
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1 Cited Publications
Cat. No.: HY-156685
CAS No.: 2767264-57-1
Purity:  99.86%
Target:  

PI4K Parasite

Research Areas:  

Infection Metabolic Disease Cancer

EDI048 is an orally active, gut-restricted parasiticidal agent. EDI048 specifically binds to the ATP-binding site of Cryptosporidium phosphatidylinositol 4-kinase (CpPI (4) K), blocks parasite membrane biogenesis, arrests the pathogen at the schizont stage, and thus irreversibly clears the infection. EDI048 is rapidly converted to an inactive carboxylic acid metabolite via hepatic first-pass metabolism, with extremely low systemic exposure, good safety profile, and no cardiotoxicity, genotoxicity or off-target effects. EDI048 is used in studies of intestinal cryptosporidiosis in children .
1
Eritadenine
Eritadenine
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1 Cited Publications
Cat. No.: HY-114866
CAS No.: 23918-98-1
Purity:  97.9%
Synonyms: Lentinacin; D-Eritadenine; Lentysine
Target:  

Parasite Nucleoside Antimetabolite/Analog

Research Areas:  

Infection

Eritadenine (D-Eritadenine) is a potent AdoHcyase inhibitor, with an IC50 value of 7 nM. Eritadenine is also an acyclic sugar adenosine analogue. Eritadenine exhibits an inhibitory effect on the growth of Cryptosporidium parvum, with a MIC50 of 3 μM. Eritadenine can be used in the research of colorectal adenocarcinoma .
Isomaltose
Isomaltose
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Cat. No.: HY-N3018
CAS No.: 499-40-1
Synonyms: 6-O-α-D-Glucopyranosyl-D-glucose; D-Isomaltose
Category:  

Human Gut Microbiota Metabolites Polysaccharides Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides

Target:  

Endogenous Metabolite Parasite

Isomaltose (6-O-α-D-Glucopyranosyl-D-glucose) is a glucose disaccharide. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection .
2-Fluoroadenosine
2-Fluoroadenosine
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Cat. No.: HY-W011517
CAS No.: 146-78-1
Synonyms: 2FA
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions .
AN7973
AN7973
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Cat. No.: HY-128337
CAS No.: 1620899-32-2
Purity:  99.37%
Target:  

Parasite

Research Areas:  

Infection

AN7973 is the 6-carboxamide benzoxaborole, blocks intracellular parasite development and inhibits Cryptosporidium growth. AN7973 is orally active, possesses favorable safety, stability, and PK parameters, and is an exciting agent candidate for treating cryptosporidiosis.
Paromomycin
Paromomycin
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Cat. No.: HY-B0956A
CAS No.: 7542-37-2
Synonyms: Aminosidine
Category:  

Microorganisms Antibiotics Other Antibiotics

Target:  

Bacterial Parasite Endogenous Metabolite

Paromomycin (Aminosidine) is an orally active broad-spectrum aminoglycoside aminocyclitol. Paromomycin is produced by Streptomyces riomosus var. Paromomycinus. Paromomycin binding induces local conformational changes in the 16S rRNA A-site. Paromomycin exhibits inhibitory activity against C. parvum. Paromomycin can be used in research related to leishmaniasis, amoebiasis and cryptosporidiosis .
KDU731
KDU731
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Cat. No.: HY-103583
CAS No.: 1610610-48-4
Purity:  99.52%
Target:  

PI4K Parasite

Research Areas:  

Infection

KDU731, an orally active C. parvum PI4K inhibitor with an IC50 value of 25 nM, blocks Cryptosporidium infection in vitro and in vivo . KDU731 is a promising agent candidate for the treatment of diarrhea caused by Cryptosporidium and meets a broad range of safety .
IMPDH-IN-3
IMPDH-IN-3
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Cat. No.: HY-128214
CAS No.: 401822-29-5
Target:  

IMPDH Parasite

Research Areas:  

Infection

IMPDH-IN-3 (Compound C67) is an inhibitor of C. parvum IMPDH (CpIMPDH) with an IC50 of 35 nM. IMPDH-IN-3 can be used in the research of anti-Cryptosporidium drugs .
DDD489
DDD489
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Cat. No.: HY-168569
CAS No.: 3003871-42-6
Target:  

Aminoacyl-tRNA Synthetase

Research Areas:  

Infection

DDD489 is a potent and selective Cryptosporidium lysyl-tRNA synthetase (CpKRS) inhibitor with IC50 values of 0.85 uM.DDD489 shows anti-cryptosporidials activity in vitro and in vivo .
Tizoxanide-d4 glucuronide
Tizoxanide-d4 glucuronide
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Cat. No.: HY-136307S
Tizoxanide-d4 glucuronide is the deuterium labeled Tizoxanide glucuronide. Tizoxanide glucuronide is the metabolite of Nitazoxanide (HY-B0217) and is cell-permeable to inhibit asexual and sexual stages development of parasite C. parvum .
MMV665917
MMV665917
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Cat. No.: HY-165555
CAS No.: 904576-65-4
Target:  

Parasite

Research Areas:  

Infection

MMV665917 is an orally active piperazine derivative with anti-Cryptosporidium parvum activity with an EC90 of 15 μM. MMV665917 significantly reduces the parasite load in a porcine model infected with C. hominis, decreases ovarian excretion, alleviates diarrhea symptoms and reduces intestinal mucosal damage. MMV665917 can be used for research on Cryptosporidium parvum disease .
2-Fluoroadenosine (Standard)
2-Fluoroadenosine (Standard)
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Cat. No.: HY-W011517R
CAS No.: 146-78-1
Synonyms: 2FA (Standard)
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions .
Nullscript
Nullscript
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Cat. No.: HY-118421
CAS No.: 300816-11-9
Target:  

Parasite HDAC

Research Areas:  

Infection

Nullscript is a negative control for Scriptaid. Nullscript is a known inactive analog of Scriptaid . Scriptaid is a representative HDAC inhibitor . Nullscript inhibits Cryptosporidium (C. parvum) growth with the IC50 value of 2.1 μM .
A110
A110
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Cat. No.: HY-120489
CAS No.: 1185388-35-5
Target:  

Parasite

Research Areas:  

Infection

A110 is the inhibitor for Cryptosporidium parvum inosine monophosphate dehydrogenase (CpIMPDH). A110 inhibits CpIMPDH in Toxoplasma gondii with IC50 of 18 nM. A110 exhibits pro-parasitic efficacy and cause parasitemia .
SLU-10482
SLU-10482
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Cat. No.: HY-158776
CAS No.: 2755451-45-5
Target:  

Parasite

Research Areas:  

Infection

SLU-10482 is an orally active anti-parasitic agent, that inhibits Cryptosporidium parvum with an IC50 of 0.0687 μM. SLU-10482 exhibits anti-infective efficacy in C. parvum infected mice with an AC50 of 0.0686 μM .
LN002
LN002
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Cat. No.: HY-162903
CAS No.: 321372-40-1
Target:  

Parasite

Research Areas:  

Infection

LN002 is an orally active anti-Cryptosporidium oxidase inhibitor for the study of cryptosporidiosis .
Isomaltose (Standard)
Isomaltose (Standard)
0 Images
Cat. No.: HY-N3018R
CAS No.: 499-40-1
Synonyms: 6-O-α-D-Glucopyranosyl-D-glucose (Standard); D-Isomaltose (Standard)
Category:  

Human Gut Microbiota Metabolites Polysaccharides Microorganisms Endogenous metabolite Saccharides

Target:  

Reference Standards Endogenous Metabolite Parasite

Isomaltose (Standard) is the analytical standard of Isomaltose (HY-N3018). This product is intended for research and analytical applications. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection .
Assay Types