904576-65-4
904576-65-4
Chemical Structure
MMV665917
- CAS No.: 904576-65-4
- Formula:C16H16ClN7O
- Molecular Weight:357.80
InChIKey: ZDXWENNHTOBFEW-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C([H])=C1)Cl)N2CCN(CC2)C3=NN4C(C=C3)=NN=C4
Biological Activity: MMV665917 is an orally active piperazine derivative with anti-Cryptosporidium parvum activity with an EC90 of 15 μM. MMV665917 significantly reduces the parasite load in a porcine model infected with C. hominis, decreases ovarian excretion, alleviates diarrhea symptoms and reduces intestinal mucosal damage. MMV665917 can be used for research on Cryptosporidium parvum disease[1].
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MMV665917 | MMV665917 is an orally active piperazine derivative with anti-Cryptosporidium parvum activity with an EC90 of 15 μM. MMV665917 significantly reduces the parasite load in a porcine model infected with C. hominis, decreases ovarian excretion, alleviates diarrhea symptoms and reduces intestinal mucosal damage. MMV665917 can be used for research on Cryptosporidium parvum disease. | |||||||||||||||||||||
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References
Keywords
