76896-80-5
Chemical Structure
Triacsin C
Synonym(s): WS 1228A; FR 900190
- CAS No.: 76896-80-5
- Formula:C11H17N3O
- Molecular Weight:207.27
IUPAC Name: N'-((1E,2E,4E,7E)-undeca-2,4,7-trien-1-ylidene)nitrous hydrazide
InChIKey: NKTGCVUIESDXPU-YLEPRARLSA-N
SMILES: CCC/C=C/C/C=C/C=C/C=N/NN=O
Biological Activity: Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C exhibits highly inhibitory effect against rotavirus replication[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Triacsin C | 98.71% | Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity. Triacsin C exhibits highly inhibitory effect against rotavirus replication. | ||||||||||||||||||||
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- [1]. Dechandt CRP, et al. Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr. 2017 Oct;49(5):399-411. [Content Brief]
- [2]. Kim Y, et al. Novel triacsin C analogs as potential antivirals against rotavirus infections. Eur J Med Chem. 2012 Apr;50:311-8. [Content Brief]
Keywords
