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Referencia número: HY-W032013S3

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1-Octanol-d₅

(Synonyms: Octanol-d₅)

1-Octanol-d₅ is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties.

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No. CAS: 3028869-76-0
Fòrmula: C₈H₁₃D₅O
Peso molecular:135.26

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

1-Octanol-d₅ Chemical Structure

No. CAS: 3028869-76-0

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Descripciòn

1-Octanol-d₅ is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents^[1]. 1-Octanol is a highly attractive biofuel with diesel-like properties^[2].

Ver todos los productos específicos de isoformas Calcium Channel :

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In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
1-octanol inhibits native T-currents at subanesthetic concentrations with an IC₅₀ of approximately 4 μM. In contrast, 1-octanol is up to 30-fold less potent in inhibiting recombinant Ca_V3.3 T-channels heterologously expressed in human embryonic kidney cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aplicación

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

No. CAS 3028869-76-0
Peso molecular 135.26
Fòrmula C₈H₁₃D₅O
SMILES

OCCCCCCC([2H])([2H])C([2H])([2H])[2H]
Synonyms

Octanol-d₅
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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1-Octanol-d5

Ver todos los productos específicos de isoformas Calcium Channel

Ver todos los productos específicos de isoformas Endogenous Metabolite

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1-Octanol-d5 Related Classifications

HY-W032013S3 Related Classifications

1-Octanol-d₅

1-Octanol-d₅ Related Classifications