Cyazofamid
Based on 1 Customer Validation
Cyazofamid exerts its bactericidal effect by impairing ATP production. Cyazofamid inhibits organic cation transporter 3 (OCT3) and OAT1, with IC50 values of 1.54 and 17.3 μM, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.15%
- No. CAS: 120116-88-3
- Fòrmula: C13H13ClN4O2S
- Peso molecular:324.79
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Transcription Factor-Targeted Library
HY-L090
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Bioactive Compound Library
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Pesticide Compound Library
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High-Throughput Bioactive Compound Library
HY-L205
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MCE Kinase Hinge Binder Fragment Library
HY-L907
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HY-L034M
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Anti-Infection Compound Library
HY-L002
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Membrane Transporter/Ion Channel Compound Library
HY-L011
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Stem Cell Signaling Compound Library
HY-L017
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Anti-Aging Compound Library
HY-L034
Actividad biológica
Chemical Information
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No. CAS 120116-88-3
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Appearance Solid
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Peso molecular 324.79
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Fòrmula C13H13ClN4O2S
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Color White to off-white
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SMILES
N#CC1=NC(Cl)=C(N1S(=O)(N(C)C)=O)C2=CC=C(C)C=C2
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Synonyms
IKF-916
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 20 mg/mL (61.58 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
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Ficha de datos (281 KB)
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SDS (458 KB)
- English - EN (458 KB)
- Français - FR (458 KB)
- Deutsch - DE (458 KB)
- Norwegian - NO (458 KB)
- Español - ES (458 KB)
- Swedish - SV (458 KB)
- Italian - IT (458 KB)
- Korean - KR (458 KB)
- Portuguese - PT (458 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Song IS, et al. Interactions between cyazofamid and human drug transporters. J Biochem Mol Toxicol. 2020 Apr;34(4):e22459. [Content Brief]
[2]. Mitani S, et al. Biological properties of the novel fungicide cyazofamid against Phytophthora infestans on tomato and Pseudoperonospora cubensis on cucumber. Pest Manag Sci. 2002 Feb;58(2):139-45. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0789 mL | 15.3946 mL | 30.7891 mL | 76.9728 mL |
| 5 mM | 0.6158 mL | 3.0789 mL | 6.1578 mL | 15.3946 mL | |
| 10 mM | 0.3079 mL | 1.5395 mL | 3.0789 mL | 7.6973 mL | |
| 15 mM | 0.2053 mL | 1.0263 mL | 2.0526 mL | 5.1315 mL | |
| 20 mM | 0.1539 mL | 0.7697 mL | 1.5395 mL | 3.8486 mL | |
| 25 mM | 0.1232 mL | 0.6158 mL | 1.2316 mL | 3.0789 mL | |
| 30 mM | 0.1026 mL | 0.5132 mL | 1.0263 mL | 2.5658 mL | |
| 40 mM | 0.0770 mL | 0.3849 mL | 0.7697 mL | 1.9243 mL | |
| 50 mM | 0.0616 mL | 0.3079 mL | 0.6158 mL | 1.5395 mL | |
| 60 mM | 0.0513 mL | 0.2566 mL | 0.5132 mL | 1.2829 mL |
Cyazofamid Related Classifications
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