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Referencia número: HY-151352

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DHDPS-IN-1

DHDPS-IN-1 (compound 8) is a DHDPS inhibitor (IC₅₀: 39 μM). DHDPS-IN-1 can be used in the area of antibacterial and herbicidal.

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No. CAS: 1233344-34-7
Fòrmula: C₁₃H₁₁NO₅S
Peso molecular:293.30

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

DHDPS-IN-1 Chemical Structure

No. CAS: 1233344-34-7

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

DHDPS-IN-1 (compound 8) is a DHDPS inhibitor (IC₅₀: 39 μM). DHDPS-IN-1 can be used in the area of antibacterial and herbicidal^[1].

IC₅₀ & Target

DHDPS^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>500 μM Compound: 6h	Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34826680]
HepG2	EC₅₀	>500 μM Compound: 6h	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34826680]

Chemical Information

No. CAS 1233344-34-7
Peso molecular 293.30
Fòrmula C₁₃H₁₁NO₅S
SMILES

COC1=CC=C(C=C1)/C=C2SC(N(C\2=O)CC(O)=O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Rebecca M Christoff, et al. Synthesis and structure-activity relationship studies of 2,4-thiazolidinediones and analogous heterocycles as inhibitors of dihydrodipicolinate synthase. Bioorg Med Chem. 2021 Dec 15;52:116518. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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