DQn-1
DQn-1 is a potent antifolate with activity against Mycobacterium tuberculosis (Mtb) (MIC90=0.03 µM). DQn-1 directly inhibits DHFR enzyme activity, with IC50s of 8.7 and 7.6 nM for Mtb and human DHFR enzyme, respectively.
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- No. CAS: 57343-54-1
- Fòrmula: C16H14ClN5O2
- Peso molecular:343.77
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
DQn-1 inhibits Mycobacterium tuberculosis, with MIC90s of 0.03 µM and 1 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 57343-54-1
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Peso molecular 343.77
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Fòrmula C16H14ClN5O2
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SMILES
O=C(C1=CC=C(NCC2=CC=C3N=C(N)N=C(C3=C2Cl)N)C=C1)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DQn-1 Related Classifications
HY-154807 Related Classifications
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