Forasartan
Forasartan is an nonpeptide angiotensin AT1 receptor antagonist with an IC50 of 2.9 nM. Forasartan is also an anti-hypertension agent. Forasartan significantly inhibits preganglionic stimulation in a dose-dependent manner in vivo. Forasartan can inhibit the heart rate increase induced by angiotensin II.
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- No. CAS: 145216-43-9
- Fòrmula: C23H28N8
- Peso molecular:416.52
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Chemical Information
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No. CAS 145216-43-9
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Peso molecular 416.52
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Fòrmula C23H28N8
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SMILES
CCCCC1=NC(CCCC)=NN1CC2=CN=C(C3=CC=CC=C3C4=NNN=N4)C=C2
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Synonyms
SC-52458
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Tokunaga, R., et al., (2001). Possible involvement of calcium-calmodulin pathways in the positive chronotropic response to angiotensin II on the canine cardiac sympathetic ganglia. Japanese journal of pharmacology, 86(4), 381-389. [Content Brief]
[2]. Gul, F., Parvaiz, N., & Azam, S. S. (2023). Deciphering the relational dynamics of AF-2 domain of PAN PPAR through drug repurposing and comparative simulations. PloS one, 18(3), e0283743. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Forasartan Related Classifications
HY-A0224 Related Classifications
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