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Referencia número: HY-161218

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HSD17B13-IN-17

HSD17B13-IN-17 (compound 9) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC₅₀ of ＜ 0.1 μM and? ＜ 1 μM estradiol and Leukotriene B3 as substrates, respectively. HSD17B13-IN-17? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis).

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No. CAS: 2758802-10-5
Fòrmula: C₂₀H₁₆ClFN₂O₃S
Peso molecular:418.87

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

HSD17B13-IN-17 Chemical Structure

No. CAS: 2758802-10-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas 17β-HSD :

17β-HSD5/AKR1C3

Chemical Information

No. CAS 2758802-10-5
Peso molecular 418.87
Fòrmula C₂₀H₁₆ClFN₂O₃S
SMILES

OC1=C(Cl)C=C(C(NC2=C(C(NCCC3=C(F)C=CC=C3)=O)SC=C2)=O)C=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Inipharm, Inc. Preparation of thiophene carboxamides as HSD17β13 inhibitors and uses thereof. World Intellectual Property Organization, WO2022020714 A1 2022-01-27

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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HSD17B13-IN-17

Ver todos los productos específicos de isoformas 17β-HSD

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

HSD17B13-IN-17 Related Classifications

HY-161218 Related Classifications