Keap1-Nrf2-IN-24
Keap1-Nrf2-IN-24 (compound 57) is a potent Keap1-Nrf2 inhibitor with a Ki value of 13 nM. Keap1-Nrf2-IN-24 increases the protein expression of TRXR1 and NQO1. Keap1-Nrf2-IN-24 increases the AKR1B10 mRNA expression. Keap1-Nrf2-IN-24 shows good metabolic stability.
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- Fòrmula: C32H25FN4O5S
- Peso molecular:596.63
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Ki: 13 nM (Keap1-Nrf2)[1]
Chemical Information
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Peso molecular 596.63
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Fòrmula C32H25FN4O5S
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SMILES
O=C(C(NC(C1=CC=CC2=C1C3=C(C=CC=C3)N2C)=O)C4=CC5=C(CCN(C5)S(=O)(C6=CC=C(C(C#N)=C6)F)=O)C=C4)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keap1-Nrf2-IN-24 Related Classifications
HY-168526 Related Classifications
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