m-PEG12-acid
Based on 1 Customer Validation
m-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureza: 99.12%
- No. CAS: 2135793-73-4
- Fòrmula: C26H52O14
- Peso molecular:588.68
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas PROTAC Linkers
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Actividad biológica
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2135793-73-4
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Appearance Solid
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Peso molecular 588.68
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Fòrmula C26H52O14
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Color Colorless to off-white
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SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 100 mg/mL (169.87 mM; ultrasonic and warming and heat to 54°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6987 mL | 8.4936 mL | 16.9872 mL | 42.4679 mL |
| 5 mM | 0.3397 mL | 1.6987 mL | 3.3974 mL | 8.4936 mL | |
| 10 mM | 0.1699 mL | 0.8494 mL | 1.6987 mL | 4.2468 mL | |
| 15 mM | 0.1132 mL | 0.5662 mL | 1.1325 mL | 2.8312 mL | |
| 20 mM | 0.0849 mL | 0.4247 mL | 0.8494 mL | 2.1234 mL | |
| 25 mM | 0.0679 mL | 0.3397 mL | 0.6795 mL | 1.6987 mL | |
| 30 mM | 0.0566 mL | 0.2831 mL | 0.5662 mL | 1.4156 mL | |
| 40 mM | 0.0425 mL | 0.2123 mL | 0.4247 mL | 1.0617 mL | |
| 50 mM | 0.0340 mL | 0.1699 mL | 0.3397 mL | 0.8494 mL | |
| 60 mM | 0.0283 mL | 0.1416 mL | 0.2831 mL | 0.7078 mL | |
| 80 mM | 0.0212 mL | 0.1062 mL | 0.2123 mL | 0.5308 mL | |
| 100 mM | 0.0170 mL | 0.0849 mL | 0.1699 mL | 0.4247 mL |
m-PEG12-acid Related Classifications
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