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United States

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Referencia número: HY-N19153

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Minimolide L

Minimolide L is a sesquiterpene lactone. Minimolide L can be isolated from the whole plant of Centipeda minima. Minimolide L does not inhibit nitric oxide production. Minimolide L exhibits no anticancer activity against liver cancer, colorectal cancer, and cervical cancer.

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No. CAS: 2629213-38-1
Fòrmula: C₂₁H₃₀O₆
Peso molecular:378.47

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Minimolide L Chemical Structure

No. CAS: 2629213-38-1

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Actividad biológica
- Descripciòn
- Cellular Effect
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	10 μM Compound: 4	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33533247]

In Vitro

Minimolide L (0.19-40 μM; 48 h) is inactive against Hela, HCT-116, and HepG2 cells, with an IC₅₀ >10 μM for all tested cell lines^[1].
Minimolide L (0.066-50 μM; 24 h) is inactive against nitric oxide production in lipopolysaccharide-activated RAW 264.7 cells, with an IC₅₀ >10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

Hela human cervical carcinoma cells, HCT-116 human colon carcinoma cells, HepG2 human liver hepatocellular carcinoma cells
Concentration:

0.19-40 μM
Incubation Time:

48 h
Result:

Exhibited no cytotoxic activity against Hela, HCT-116, and HepG2 cells, with an IC₅₀ value greater than 10 μM for all three cell lines.

Chemical Information

No. CAS 2629213-38-1
Peso molecular 378.47
Fòrmula C₂₁H₃₀O₆
SMILES

C[C@]12[C@@H](OC(/C(=C\C)/C)=O)[C@]3([C@@](C[C@@H](C)[C@@]1([C@H](OC)CC2=O)[H])(OC(=O)[C@H]3C)[H])[H]
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Xue PH, et al. Cytotoxic and Anti-Inflammatory Sesquiterpenes from the Whole Plants of Centipeda minima. J Nat Prod. 2021 Feb 26;84(2):247-258. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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