MPO-IN-6
MPO-IN-6 (compound ADC) is an electrophile with good antioxidant and anti-inflammatory properties. MPO-IN-6 is a myeloperoxidase (MPO), dipeptidyl peptidase-4 (DPP-4), and α-glucosidase (α-GD) inhibitor with IC50s of 10 μM, 31.02 μM, and 46.05 μM, respectively. MPO-IN-6 is a potential cardiovascular preventive agent.
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- Fòrmula: C16H12N2O6
- Peso molecular:328.28
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Myeloperoxidase 10 μM (IC50) |
DPP-4 31.02 μM (IC50) |
α-Glucosidase 46.05 μM (IC50) |
From DPPH and ABTS•+ scavenging assay results, the corresponding IC50 values for MPO-IN-6 (compound ADC) are 41.04 μM and 66.13 μM, respectively[1].
At a concentration of 10 mM, MPO-IN-6 (compound ADC) demonstrates 35% α-glucosidase (α-GD) inhibition, and as the concentration increased, the activity is found to increase by 81%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 328.28
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Fòrmula C16H12N2O6
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SMILES
O=C(C1=C([N+]([O-])=O)C=C(OCO2)C2=C1)NC3=CC=CC(C(C)=O)=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MPO-IN-6 Related Classifications
HY-163332 Related Classifications
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