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Referencia número: HY-170544

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RIPK1-IN-28

RIPK1-IN-28 (compound 13) is an orally active RIPK1 inhibitor. RIPK1-IN-28 inhibits human I2.1 and Hepa1‐6 cells with IC₅₀s of 0.4 and 1.2 nM, respectively.

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No. CAS: 2968509-28-4
Fòrmula: C₂₇H₂₄N₄O₄
Peso molecular:468.50

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

RIPK1-IN-28 Chemical Structure

No. CAS: 2968509-28-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

RIPK1-IN-28 (compound 13) is an orally active RIPK1 inhibitor. RIPK1-IN-28 inhibits human I2.1 and Hepa1‐6 cells with IC₅₀s of 0.4 and 1.2 nM, respectively^[1].

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Chemical Information

No. CAS 2968509-28-4
Peso molecular 468.50
Fòrmula C₂₇H₂₄N₄O₄
SMILES

CN1C2=CC(C#CC3CC3)=CC=C2OC[C@@H](C1=O)NC(C4=NN(C5=CC=CC=C5)C(C)=CC4=O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. An Y, et al. Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors. Arch Pharm (Weinheim). 2025 Jan;358(1):e2400594. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RIPK1-IN-28

Ver todos los productos específicos de isoformas RIP kinase

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

RIPK1-IN-28 Related Classifications

HY-170544 Related Classifications