RIPK3-IN-2
RIPK3-IN-2 is a RIP3 inhibitor. RIPK3-IN-2 can be used in diseases caused by or associate with activated necrotic pathways research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2665669-32-7
- Fòrmula: C21H16ClN3O2S2
- Peso molecular:441.95
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
RIPK3-IN-2 (0.3-20 μM; 42 h) inhibits HT-29 cell growth[1].
RIPK3-IN-2 (0.3-20 μM; 14 h) inhibits MEF cell growth[1].
RIPK3-IN-2 (0.3-20 μM; 18 h) inhibits L929 cell growth[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HT-29 cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:42 hours
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Result:Showed EC50 value of 0.085 μM.
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Cell Line:MEF cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:14 hours
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Result:Showed EC50 value of 0.24 μM.
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Cell Line:L929 cells
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Concentration:0.3, 1.0, 3.0, 10.0, 20.0 μM
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Incubation Time:18 hours
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Result:Showed EC50 value of 0.21 μM.
Chemical Information
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No. CAS 2665669-32-7
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Peso molecular 441.95
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Fòrmula C21H16ClN3O2S2
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SMILES
O=S1(C=C(C2CC2)C3=C1C=C4C(NC5=CC6=C(SC=N6)C=C5)=CC=NC4=C3)=O.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)