RIPK3-IN-7
RIPK3-IN-7 is a RIPK3 inhibitor that suppresses the RIPK3-mediated necroptosis pathway. RIPK3-IN-7 can be used for research on necroptosis and inflammation-related diseases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3116772-57-4
- Fòrmula: C24H25N3O2S2
- Peso molecular:451.60
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
RIPK3-IN-7 (LK-18) (20 μM) inhibits RIPK3-mediated necrosis in L929 cells and HT29 cells, with an EC50 of 1.2 μM, has a high selectivity ratio (CC50/EC50) of 44.3, and does not induce Caspase-3 activation at 20 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3116772-57-4
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Peso molecular 451.60
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Fòrmula C24H25N3O2S2
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SMILES
O=S(=O)(C=1C=CC2=NC=CC(NC=3C=CC=4SC(=NC4C3)C5CCCC5)=C2C1)C(C)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)