UCM-13369
UCM-13369 (Compound 4b) is a NPM1 inhibitor. UCM-13369 downregulates the pathway associated with mutant NPM1 C+, and specifically recognizes the C-end DNA-binding domain of NPM1 C+. UCM-13369 induces apoptosis in AML cell lines and primary cells, that can be used for the research of AML.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2921944-77-4
- Fòrmula: C25H31N3O
- Peso molecular:389.53
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
NPM1[1]
Chemical Information
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No. CAS 2921944-77-4
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Peso molecular 389.53
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Fòrmula C25H31N3O
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SMILES
N[C@@H]([C@@H]1CCNCC2CC2)[C@@H](C3=CC=C(OC)C=C3)CC4=C1C5=C(N4)C=CC=C5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UCM-13369 Related Classifications
HY-162265 Related Classifications
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